Cause of parkinsonian symptoms: Firing rate, firing pattern or dynamic activity changes?
نویسندگان
چکیده
منابع مشابه
A firing rate model of Parkinsonian deficits in interval timing.
To account for deficits in interval timing observed in Parkinson's Disease (PD) patients, we develop a model based on the accumulating firing rate of a neural population with recurrent excitation. This model naturally produces the curvilinear accumulation of neural activity introduced to timing psychophysics by Miall (Models of Neural Timing, Elsevier Science, 1996), and implicated in Parkinson...
متن کاملStochastic firing rate models
We review a recent approach to the mean-field limits in neural networks that takes into account the stochastic nature of input current and the uncertainty in synaptic coupling. This approach was proved to be a rigorous limit of the network equations in a general setting, and we express here the results in a more customary and simpler framework. We propose a heuristic argument to derive these eq...
متن کاملEstimating the Firing Rate
Neuronal activity is measured by the number of stereotyped action potentials, called spikes, elicited in response to a stimulus or the behavioral conditions of an animal. Any nonparametric method for grasping the time-varying rate of spike firing contains a single parameter that controls the jaggedness of the estimated rate, such as the binsize of the time histogram or the bandwidth of the kern...
متن کاملFiring rate and firing synchrony distinguish dynamic from steady state sound.
The role of firing-rate and firing synchrony within and between three auditory cortical areas in coding complex sounds was investigated. In cortex, steady-state sound rarely caused any difference in firing rate over the spontaneous rate, but induced greater neural synchrony within and between cortical areas than were present during silence. Dynamic changes, other than onsets, produced similar s...
متن کاملFigure S2. Hypothetical Firing Rate
the value of good X (x-axis) and such that the response is menu dependent (red when X is offered against Y, blue when X is offered against Z). Transitivity violations (i.e., cases where x-axis orderings are not conserved on the y-axis) are possible, as for X1, X2, X3. However, if the representation is menu invariant (i.e., if red and blue lines coincide), transitivity violations cannot occur. I...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Basal Ganglia
سال: 2015
ISSN: 2210-5336
DOI: 10.1016/j.baga.2014.11.001